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Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders.

P AuvinenJ VehviläinenH MarjonenV ModhukurJ SokkaE WallénK RämöL AholaA SalumetsT OtonkoskiH SkottmanM OllikainenR TrokovicH KahilaNina Kaminen-Ahola
Published in: BMC medicine (2022)
Our study shows the effects of early alcohol exposure on human embryonic and extraembryonic cells, introduces candidate genes for alcohol-induced developmental disorders, and reveals potential biomarkers for prenatal alcohol exposure.
Keyphrases
  • alcohol consumption
  • high glucose
  • endothelial cells
  • diabetic rats
  • genome wide
  • pregnant women
  • dna damage
  • transcription factor
  • dna methylation
  • induced pluripotent stem cells
  • embryonic stem cells