Mesenchymal stem cell transplantation after acute myocardial infarction: a meta-analysis of clinical trials.
Armin AttarFateme Bahmanzadegan JahromiShahin KavousiAhmad MonabatiAsma KazemiPublished in: Stem cell research & therapy (2021)
Transplantation of MSCs after AMI significantly increases LVEF, showing a higher efficacy if done in the first week. Further clinical studies should be conducted to investigate long-term clinical outcomes such as heart failure and cardiovascular mortality.
Keyphrases
- acute myocardial infarction
- mesenchymal stem cells
- heart failure
- clinical trial
- left ventricular
- cell therapy
- percutaneous coronary intervention
- umbilical cord
- cardiovascular events
- bone marrow
- coronary artery disease
- atrial fibrillation
- risk factors
- cardiac resynchronization therapy
- cardiovascular disease
- stem cells
- phase ii
- open label