Vaccine based on folded receptor binding domain-PreS fusion protein with potential to induce sterilizing immunity to SARS-CoV-2 variants.

Pia Gattinger Bernhard Kratzer Inna Tulaeva Katarzyna Niespodziana Anna Ohradanova-Repic Laura GebetsbergerKristina BorochovaErika Garner-SpitzerDoris TrapinGerhard HoferWalter KellerIsabella BaumgartnerAmra Tancevski Khaitov M RAlexander KaraulovHannes Stockinger Ursula Wiedermann Winfried F Pickl Rudolph Valenta

Published in: Allergy (2022)

The PreS-RBD vaccine has the potential to serve as a combination vaccine for inducing sterilizing immunity against SARS-CoV-2 and HBV by stopping viral replication through the inhibition of cellular virus entry.

Keyphrases

sars cov
respiratory syndrome coronavirus
hepatitis b virus
human health
gene expression
risk assessment
binding protein
climate change