PGD 2 /DP1 axis promotes liver regeneration by secreting Wnt2 in KCs in mice.

Juanjuan LiYinghong ZhengZhenzhen DuanQingye ZengJin QuJincheng ZhangJiao LiuWenlong ShangXixi TaoTingting YuXinzhi LiLifu WangLiming Yang Deping Kong Ying Yu

Published in: Hepatology (Baltimore, Md.) (2024)

DP1 activation mediates crosstalk between KCs and hepatocytes through Wnt2 and facilitates liver regeneration. Hence, DP1 may serve as a novel therapeutic target in acute and chronic liver diseases.

Keyphrases

stem cells
cell proliferation
drug induced
liver failure
liver injury
respiratory failure
metabolic syndrome
wound healing
insulin resistance
aortic dissection
extracorporeal membrane oxygenation
acute respiratory distress syndrome