Developmental system drift in motor ganglion patterning between distantly related tunicates.

Published in: EvoDevo (2018)

This acute divergence in the molecular mechanisms that underlie otherwise functionally conserved cis-regulatory DNAs supports the recently proposed idea that the extreme genetic plasticity observed in tunicates may be attributed to the extreme rigidity of the spatial organization of their embryonic cell lineages.

Keyphrases

transcription factor
climate change
liver failure
single cell
drug induced
cell therapy
respiratory failure
neuropathic pain
genome wide
copy number
stem cells
gene expression
dna methylation
spinal cord injury
acute respiratory distress syndrome