Internally Functionalized Dendrimers Based on Fully Substituted 1,2,3-Triazoles.
Lijiao NiuNingning SongXiaojun WangShengtao DingPublished in: Macromolecular rapid communications (2022)
Being one important class in dendrimer chemistry, internally functionalized dendrimers (IFDs) are still exiguous. Here, the first construction of IFDs involving fully substituted 1,2,3-triazole rings as interior functionality carriers is demonstrated. Through divergent or convergent synthetic protocols established on the efficient iridium-catalyzed annulation of internal 1-thioalkynes with organic azides, sequence-controlled heterolayered dendrimers with different branched structures are achieved in a convenient manner. 1 H NMR, mass spectrometry, and size exclusion chromatography characterizations well identify their architecture and high purity.
Keyphrases
- mass spectrometry
- high resolution
- liquid chromatography
- molecular docking
- quantum dots
- high performance liquid chromatography
- magnetic resonance
- high speed
- tandem mass spectrometry
- gas chromatography
- molecularly imprinted
- capillary electrophoresis
- room temperature
- amino acid
- solid state
- molecular dynamics simulations
- ionic liquid
- simultaneous determination