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Efficacy and safety of neoadjuvant immune checkpoint inhibitors in early-stage triple-negative breast cancer: a systematic review and meta-analysis.

Michal SternschussRinat YerushalmiRamy R SalehEitan AmirHadar Goldvaser
Published in: Journal of cancer research and clinical oncology (2021)
Combination of ICIs and NACT were associated with improved outcome in early-stage TNBC while increasing toxicity significantly. Longer follow-up is desired to better understand the risk and benefit ratio of this combination.
Keyphrases
  • early stage
  • sentinel lymph node
  • rectal cancer
  • lymph node
  • locally advanced
  • oxidative stress
  • squamous cell carcinoma
  • neoadjuvant chemotherapy
  • radiation therapy