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Tumor Necrosis Factor- α -Induced Protein 8-Like 2 Ameliorates Cardiac Hypertrophy by Targeting TLR4 in Macrophages.

Rui YaoLing-Yao KongChun-Lei YangJiaqi DuGuojun ZhaoYapeng Li
Published in: Oxidative medicine and cellular longevity (2022)
The present study indicated that TIPE2 represses macrophage activation by targeting TLR4, subsequently inhibiting cardiac hypertrophy.
Keyphrases
  • toll like receptor
  • inflammatory response
  • immune response
  • rheumatoid arthritis
  • high glucose
  • adipose tissue
  • signaling pathway
  • diabetic rats
  • nuclear factor
  • mouse model
  • binding protein
  • oxidative stress