DNA and RNA-sequence based GWAS highlights membrane-transport genes as key modulators of milk lactose content.

Thomas J LopdellKathryn TipladyMaksim StruchalinThomas J J JohnsonMichael KeehanRic SherlockChristine CouldreyStephen R DavisRussell G SnellRichard J SpelmanMathew D Littlejohn

Published in: BMC genomics (2017)

Overall, these findings highlight novel candidate genes and variants involved in milk lactose regulation, whose impacts on membrane transport mechanisms reinforce the key osmo-regulatory roles of lactose in milk.

Keyphrases

transcription factor
genome wide
copy number
circulating tumor
nucleic acid
genome wide identification