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Genetic mapping of principal components of canine pelvic morphology.

Mark J FealeyJoy LiRebel J E TodhunterUrsula KrotscheckKei HayashiMarina J McConkeyAdam R BoykoJessica J HaywardRory J Todhunter
Published in: Canine genetics and epidemiology (2017)
IGF-1 was associated with the overall size of the pelvis and sex is related to pelvic size. Ilial/ischial proportion is genetically controlled and the closest candidate gene is thiamine-dependent and affects birth weight and development of the nervous system. Dogs with larger pelves tend to have smaller NAs consistent with increased tendency toward HD in large breed dogs. Based on the current study, pelvic shape alone was not strongly associated with canine hip dysplasia.
Keyphrases
  • birth weight
  • rectal cancer
  • genome wide
  • gestational age
  • weight gain
  • copy number
  • high resolution
  • dna methylation
  • signaling pathway
  • total hip arthroplasty
  • physical activity
  • high density
  • genome wide identification