Dose-dependent cranial irradiation associations with brain structures and neuropsychological outcomes in children with posterior fossa brain tumors.
Mary C Baron NelsonSharon H O'NeilScarlet J ChoSofia DhananiJeffrey TanedoBrandon J ShinJack RodmanArthur OlchKenneth WongMarvin D NelsonJonathan FinlayNatasha LeporePublished in: Brain and behavior (2024)
All children with posterior fossa tumors, regardless of treatment modality, had cognitive deficits compared to their sibling controls. Posterior fossa irradiation may affect thalamic volume and aspects of verbal and nonverbal cognitive functioning.