Fasciola hepatica GST mu-class suppresses the cytokine storm induced by E. coli -lipopolysaccharide, whereas it modulates the dynamic of peritoneal macrophages in a mouse model and suppresses the classical activation of macrophages.
Bianca N Valdes-FernandezCaleb Ruiz-JimenezAlbersy Armina-RodriguezLoyda B MendezAna M M EspinoPublished in: Microbiology spectrum (2023)
glutathione S-transferase is a promising candidate for drug development against endotoxemia and other inflammatory diseases.