TGF-β Pathways Stratify Colorectal Cancer into Two Subtypes with Distinct Cartilage Oligomeric Matrix Protein (COMP) Expression-Related Characteristics.

Jia-Tong DingHao-Nan ZhouYing-Feng HuangJie PengHao-Yu HuangHao YiZhen ZongZhi-Kun Ning

Published in: Biomolecules (2022)

Comprehensive immune analysis and experimental validation demonstrate that COMP is a reliable signature for subtype prediction. Our results could provide a new point for TGFβ-targeted anticancer drugs and contribute to guiding clinical decision making for CRC patients.

Keyphrases

end stage renal disease
decision making
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
binding protein
patient reported outcomes
protein protein
long non coding rna
drug induced