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Sepsis and obesity: a scoping review of diet-induced obesity murine models.

Mikaela EngKeshikaa SuthaaharanLogan NewtonFatima SheikhAlison E Fox-Robichaudnull null
Published in: Intensive care medicine experimental (2024)
There is variability in the methodology and measured outcomes in murine models of diet-induced obesity and sepsis and a lack of studies in female mice. The absence of standardized models has produced conflicting findings on the impact of obesity on sepsis outcomes.
Keyphrases
  • high fat diet induced
  • insulin resistance
  • metabolic syndrome
  • weight loss
  • type diabetes
  • weight gain
  • acute kidney injury
  • intensive care unit
  • septic shock
  • adipose tissue
  • skeletal muscle
  • body mass index