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Fibroblast Growth Factor-induced lens fiber cell elongation is driven by the stepwise activity of Rho and Rac.

Yuki SugiyamaDaniel A ReedDavid HerrmannFrank J LovicuMichael L RobinsonPaul TimpsonIchiro Masai
Published in: bioRxiv : the preprint server for biology (2023)
FGF differentially regulates Rho- and Rac-activity at the lens equator to promote lens fiber cell elongation and migration.
Keyphrases
  • single cell
  • cell therapy
  • cataract surgery
  • stem cells
  • protein kinase
  • smooth muscle
  • mesenchymal stem cells
  • oxidative stress
  • drug induced
  • bone marrow