The Feasibility and Safety of Induction Chemotherapy Followed by Definitive Chemoradiation in Patients with Locally Advanced Cervical Cancer: A Single-Arm Phase II Clinical Trial.
Niloofar AhmadlooMarzieh HeidarpourfardFatemeh Sadat NajibZahra ShiravaniShapour OmidvariAhmad MosalaeiMohammad MohammadianpanahMansour AnsariHamid NasrollahiNezhat KhanjaniBehnam KadkhodaeiSayed Hasan HamediPublished in: Asian Pacific journal of cancer prevention : APJCP (2023)
Induction chemotherapy followed by chemoradiation is feasible in patients with locally advanced cervical cancer; however, the toxicity should be managed properly to avoid delayed e treatment. More than three quarters of the patients achieved complete or partial clinical response within a three-month follow-up.
Keyphrases
- locally advanced
- rectal cancer
- phase ii
- clinical trial
- neoadjuvant chemotherapy
- squamous cell carcinoma
- phase ii study
- radiation therapy
- end stage renal disease
- open label
- chronic kidney disease
- ejection fraction
- prognostic factors
- newly diagnosed
- oxidative stress
- double blind
- patient reported outcomes
- phase iii
- combination therapy