The Expanding Utility of Rhodium-Iminocarbenes: Recent Advances in the Synthesis of Natural Products and Related Scaffolds.

Rhodium-iminocarbenes that are derived from N-sulfonyl-1,2,3-triazoles have become an important class of reactive species and useful intermediates in organic synthesis. Over the last several years, many practical and versatile approaches involving rhodium-iminocarbene intermediates to synthetically challenging molecules (scaffolds) have been developed. This Minireview mainly summarizes the recent advance of rhodium-iminocarbene involved reactions in the synthesis of natural products and their related scaffolds by the end of 2017. Several applications in important pharmaceuticals are documented as well.