Escherichia coli Nissle 1917 restores epithelial permeability alterations induced by irritable bowel syndrome mediators.
M R BarbaroD FuschiCesare CremonM CarapelleP DinoM M MarcelliniG DothelF De PontiV StanghelliniGiovanni BarbaraPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
EcN reinforces the integrity of Caco-2 monolayer and reverts the increase of permeability induced by mediators released by IBS biopsies. Future studies should investigate EcN therapeutic potentials in IBS.