Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up.
Anna GrefSimon K MeridOlena GruzievaStéphane BallereauAllan BeckerTom BellanderAnna BergströmYohan BosseMatteo BottaiMoira Chan-YeungElaine FuertesDespo IerodiakonouRuiwei JiangStéphane JolyMeaghan JonesMichael S KoborMichal KorekAnita L KozyrskyjAshish KumarNathanaël LemonnierElaina MacIntyreCamille MénardDavid NickleMa'en ObeidatJohann PelletMarie StandlAnnika SääfCilla SöderhällCarla M T TieslerMaarten van den BergeJudith M VonkHita VoraCheng-Jian XuJosep M AntóCharles AuffrayMichael BrauerJean BousquetBert BrunekreefW James GaudermanJoachim HeinrichJuha KereGerard H KoppelmanDirkje PostmaChristopher CarlstenGöran PershagenErik MelénPublished in: American journal of respiratory and critical care medicine (2017)
Our results indicated that gene-environment interactions are important for asthma development and provided supportive evidence for interaction with air pollution for ADCY2, B4GALT5, and DLG2.