Exosome-Delivered EGFR Induced by Acidic Bile Salts Regulates Macrophage M2 Polarization to Promote Esophageal Adenocarcinoma Cell Proliferation.
Chuangui ChenJinsheng DingZhao MaYongjie XieLinhua ZhangDunwan ZhuPublished in: OncoTargets and therapy (2024)
Our findings demonstrate that ABS-induced exosomal EGFR regulates macrophage M2 polarization to promote EAC proliferation. This study provides an important insight into the role of ABS in EAC development.