Orphan GPCR GPRC5C Facilitates Angiotensin II-Induced Smooth Muscle Contraction.
Tianpeng WangJingchen ShaoShamit KumarMohammad Wessam AlnouriJorge CarvalhoStefan GüntherCornelius KraselKate T MurphyMoritz BünemannStefan OffermannsNina WettschureckPublished in: Circulation research (2024)
Our data show that GPRC5C regulates Ang II-dependent vascular contraction by facilitating AT1 receptor-ligand binding and signaling.