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Gynecological Cancers in Lynch Syndrome: A Comparison of the Histological Features with Sporadic Cases of the General Population.

Valentina Elisabetta BounousElisabetta RobbaStefania PerottoBarbara PasiniNicoletta Tomasi ContMaria Teresa RicciAntonino DittoVitellaro MarcoFrancesco RaspagliesiNicoletta Biglia
Published in: Journal of clinical medicine (2022)
LS-associated EC and OC seem to have peculiar features, occurring at a younger age and at an earlier stage. In LS, EC less frequently involves the outer half of the endometrium, with a more frequent occurrence in the LUS. The presence of clear cell EC was more frequently observed, whereas in OC, the predominant histotype was endometrioid.
Keyphrases
  • clear cell
  • risk assessment
  • endometrial cancer
  • case report
  • amyotrophic lateral sclerosis
  • young adults
  • early onset