Evaluation of Circulating Tumor DNA for Methylated BCAT1 and IKZF1 to Detect Recurrence of Stage II/Stage III Colorectal Cancer (CRC).
Benjamin L MusherJoshua E MelsonGianni AmatoDavid ChanMarisa HillIftekhar KhanSamith T KochuparambilSusan E LyonsJames OrsiniSusanne K PedersenBruce RobbJoel SaltzmanJennifer SilinskySnigdha GaurMelissa K TuckLawrence C LaPointeGraeme Paul YoungPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2020)
This prospective study showed that COLVERA (a two-gene ctDNA assay) was more sensitive for detection of recurrence in a cohort of patients undergoing surveillance after definitive therapy for stages II and III colorectal cancer.