Free-base porphyrins as CEST MRI contrast agents with highly upfield shifted labile protons.

Xiaoxiao ZhangYaping YuanSha LiQingbin ZengQianni GuoNa LiuMinghui YangYunhuang YangMaili LiuMichael T McMahonXin Zhou

Published in: Magnetic resonance in medicine (2019)

These results highlight the capabilities of free-base porphyrins and chlorin as highly upfield CEST MRI agents and provide a new scaffold that can be integrated into a variety of diagnostic or theranostic agents for biomedical applications.

Keyphrases

contrast enhanced
photodynamic therapy
magnetic resonance imaging
magnetic resonance
diffusion weighted imaging
computed tomography