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Drug-Polymer Interaction, Pharmacokinetics and Antitumor Effect of PEG-PLA/Taxane Derivative TM-2 Micelles for Intravenous Drug Delivery.

Qiao WangYi LiuChenguang PuHongjuan ZhangXinyi TanJingxin GouHaibing HeTian YinYu ZhangYanjiao WangXing Tang
Published in: Pharmaceutical research (2018)
TM-2 micelles with high drug loading increased drug solubility, improved tolerance, antitumor effects and reduced toxicity.
Keyphrases
  • drug delivery
  • cancer therapy
  • drug release
  • adverse drug
  • oxidative stress
  • high dose
  • low dose
  • hyaluronic acid