Paraneoplastic cerebellar ataxia and antibodies to metabotropic glutamate receptor 2.

Raquel Ruiz GarcíaEugenia Martínez-HernándezBastien JoubertMar Petit-PedrolElena Pajarón-BoixVerónica FernándezLidia SalaisMaría Del PozoThais ArmanguéLidia SabaterJosep DalmauFrancesc Graus

Published in: Neurology(R) neuroimmunology & neuroinflammation (2019)

mGluR2-Abs are a novel biomarker of paraneoplastic cerebellar ataxia. The potential pathogenic effect of the antibodies is not mediated by downregulation or internalization of neuronal surface mGluR2.

Keyphrases

early onset
cell proliferation
signaling pathway
human health
risk assessment
binding protein
subarachnoid hemorrhage