Comparison of High-Resolution Melting (HRM) Analysis with Direct Sequencing for the Detection of DNMT3A Mutations in AML Patients.

Mohammadreza MoonesiSaeed Zaka KhosraviAlireza MoradabadiMohsen RajaeinejadMohammad Foad HeidariGolnoosh MahjubAli Noroozi-Aghideh

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

According to the full consistency between the HRM and direct sequencing methods, HRM is suggested to be adopted as an alternative for the common time-consuming methods in detecting the gene mutations.

Keyphrases

high resolution
end stage renal disease
ejection fraction
single cell
newly diagnosed
acute myeloid leukemia
dna methylation
prognostic factors
mass spectrometry
gene expression
patient reported outcomes
allogeneic hematopoietic stem cell transplantation
high speed
data analysis
liquid chromatography