Impact of Autologous Transplantation in Patients with Multiple Myeloma with t(11;14): A Propensity-Score Matched Analysis.

Neeraj SainiJunsheng MaDenái R MiltonRomil PatelAnkur VarmaQaiser BashirRuby DelgadoAkash MukherjeeGabriela RondonUday R PopatChitra M HosingYago L NietoPartow KebriaeiAmin M AlousiSairah A AhmedGuilin TangRohtesh MehtaSamer SrourIssa F KhouriSwaminathan IyerDonna M WeberSheeba K ThomasHans C LeeElisabet E ManasanchKrina K PatelRobert Z OrlowskiRichard E ChamplinMuzaffar H Qazilbash

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Our study confirms that t(11;14) multiple myeloma undergoing upfront autologous transplantation had similar outcomes as patients with multiple myeloma with normal cytogenetic and FISH studies. Existence of additional genomic aberrations by CC or FISH was associated with a worse outcome.

Keyphrases

multiple myeloma
cell therapy
bone marrow
copy number
platelet rich plasma
stem cells
metabolic syndrome
adipose tissue
dna methylation