Identification of key DNA methylation changes on fasting plasma glucose: a genome-wide DNA methylation analysis in Chinese monozygotic twins.

Weijing WangWenqin YaoQihua TanShuxia LiHaiping DuanXiaocao TianChunsheng XuDongfeng Zhang

Published in: Diabetology & metabolic syndrome (2023)

We detect many DNAm variants that may be associated with FPG in whole blood, particularly the loci within SLC6A18 gene. Our findings provide important reference for the epigenetic regulation of elevated FPG levels and diabetes.

Keyphrases

genome wide
dna methylation
copy number
blood glucose
gene expression
type diabetes
cardiovascular disease
glycemic control
insulin resistance
adipose tissue
blood pressure
weight loss
bioinformatics analysis