The cytotoxic effect of TiF4 and NaF on fibroblasts is influenced by the experimental model, fluoride concentration and exposure time.
Priscila Maria Aranda SalomãoFlávia Amadeu de OliveiraPaula Danielle RodriguesLuana Polioni Al-AhjKellen Cristina da Silva GasquePia JeggleMarilia Afonso Rabelo BuzalafRodrigo Cardoso de OliveiraJohn Michael EdwardsonAna Carolina MagalhãesPublished in: PloS one (2017)
Based on the results of the 3 experimental steps, we conclude that TiF4 and NaF have similar cytotoxicity. The cytotoxicity was dependent on F concentration and exposure time. This result gives support for testing the effect of TiF4 varnish in vivo.
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