Sex-specific causality of MRI-derived body compositions on glycaemic traits: Mendelian randomization and observational study.

Yijie ZhuQi WangHuajie DaiTianzhichao HouTian-Ge WangZhiyun ZhaoMian LiWei MiaoJian YangJie-Li LuYu XuYuhong ChenGuang NingJie ZhengYufang BiYanan HouWeiqing Wang

Published in: Diabetes, obesity & metabolism (2023)

Body composition has a sex-specific effect on type 2 diabetes, and higher GFATadj has an independent protective effect on type 2 diabetes in both sexes.

Keyphrases

type diabetes
body composition
resistance training
glycemic control
bone mineral density
cardiovascular disease
magnetic resonance imaging
insulin resistance
contrast enhanced
metabolic syndrome
dna methylation
adipose tissue
magnetic resonance
postmenopausal women
skeletal muscle
electronic health record