T1/T2 ratio: A quantitative sensitive marker of brain tissue integrity in multiple sclerosis.
Salem HannounGabriel KocevarPekes CodjiaBerardino BarileFrançois CottonFrançoise Durand-DubiefDominique Sappey-MarinierPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2021)
Results showed significant differences between RRMS and HC in both DTI and T1/T2 ratio measurements. T1/T2 ratio even demonstrated extensive WM abnormalities when compared to DTI, thereby highlighting the ratio's sensitivity to subtle differences in cerebral WM structural integrity using only conventional MRI sequences.