T1/T2 ratio: A quantitative sensitive marker of brain tissue integrity in multiple sclerosis.

Salem Hannoun Gabriel Kocevar Pekes Codjia Berardino Barile François Cotton Françoise Durand-Dubief Dominique Sappey-Marinier

Published in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2021)

Results showed significant differences between RRMS and HC in both DTI and T1/T2 ratio measurements. T1/T2 ratio even demonstrated extensive WM abnormalities when compared to DTI, thereby highlighting the ratio's sensitivity to subtle differences in cerebral WM structural integrity using only conventional MRI sequences.

Keyphrases

multiple sclerosis
white matter
magnetic resonance imaging
subarachnoid hemorrhage
functional connectivity