Development of an Accelerated Rotator-based Drug Release Method for the Evaluation of Bupivacaine Multivesicular Liposomes.

Ziyun XiaMinzhi YuYayuan LiuWenmin YuanYan WangXiaoming XuJungeun BaeAnna A Schwendeman

Published in: Pharmaceutical research (2024)

An accelerated rotator-based IVRT method for bupivacaine MVLs was developed in this study, with the discriminatory ability to distinguish between formulations of different qualities. The developed IVRT method was a robust tool for generic development of MVL based formulations.

Keyphrases

drug release

drug delivery

pain management