Cytotoxicity and Apoptosis Studies of Brucein D against T24 Bladder Cancer Cells.

Pandu Ishaq NandanaHaerani RasyidPrihantono PrihantonoIka YustisiaLukman HakimAgussalim BukhariEka Sunarwidhi Prasedya

Published in: Asian Pacific journal of cancer prevention : APJCP (2024)

BrD has shown a cytotoxic effect against T24 bladder cancer cells. Hence, it is a promising natural compound for the management of bladder cancer by induction of apoptosis through activation of the intrinsic pathway, with low toxicity to normal cells.

Keyphrases

cell cycle arrest
cell death
induced apoptosis
oxidative stress
endoplasmic reticulum stress
pi k akt
spinal cord injury
urinary tract
cell proliferation