Login / Signup

N,N'-bicarbazole-benzothiadiazole-based conjugated porous organic polymer for reactive oxygen species generation in live cells.

Subhankar KunduBiswajit BeheraArkaprabha GiriNitu SahaAbhijit Patra
Published in: Chemical communications (Cambridge, England) (2021)
A π-conjugated porous organic polymer (BCzBz) was fabricated employing N,N'-bicarbazole and benzothiadiazole as molecular building units exhibiting broad visible light absorption. The photostable, water-dispersible, and cytocompatible BCzBz was demonstrated as an efficient probe for intracellular reactive oxygen species generation under photoirradiation.
Keyphrases
  • reactive oxygen species
  • visible light
  • induced apoptosis
  • photodynamic therapy
  • cell cycle arrest
  • metal organic framework
  • water soluble
  • endoplasmic reticulum stress
  • quantum dots
  • signaling pathway