Levels of human proteins in plasma associated with acute paediatric malaria.
Philippa ReuterswärdSofia BergströmJudy OrikiirizaElisabeth LindquistSven BergströmHelene Andersson SvahnBurcu AyogluMathias UhlénMats WahlgrenJohan NormarkUlf RibackePeter NilssonPublished in: Malaria journal (2018)
In this study, a high-throughput affinity proteomics approach was used to find protein profiles in plasma linked to P. falciparum infection and malaria disease progression. The proteins presented herein are mainly involved in inflammatory response, cellular adhesion and as constituents of erythrocyte membrane. These findings have a great potential to provide increased conceptual understanding of host-parasite interaction and malaria pathogenesis.
Keyphrases
- plasmodium falciparum
- inflammatory response
- high throughput
- endothelial cells
- liver failure
- mass spectrometry
- emergency department
- respiratory failure
- single cell
- drug induced
- hepatitis b virus
- amino acid
- small molecule
- toll like receptor
- protein protein
- biofilm formation
- induced pluripotent stem cells
- extracorporeal membrane oxygenation
- capillary electrophoresis
- candida albicans
- essential oil