Interaction of Isocitrate Lyase with Proteins Involved in the Energetic Metabolism in Paracoccidioides lutzii.
Kleber Santiago Freitas E SilvaRaisa Melo LimaPatrícia de Sousa LimaLilian Cristiane BaezaRoosevelt Alves Da SilvaCélia Maria de Almeida SoaresMaristela PereiraPublished in: Journal of fungi (Basel, Switzerland) (2020)
ICL seems to interfere with energetic metabolism of P. lutzii, regulating aerobic and anaerobic metabolism as it interacts with proteins from glycolysis, gluconeogenesis, TCA and methylcitrate cycles, mainly through seven hot-spot residues.