Genetically predisposed and resilient animal models of depression reveal divergent responses to early-life adversity.

Ashleigh J WhitneyZander LindequeRuan KrugerStephanus Frederik Steyn

Published in: Acta neuropsychiatrica (2023)

These findings highlight the need to further investigate the stress response pathway in these animals and that the absence or presence of genetic susceptibility may influence the presentation of early-life adversity effects.

Keyphrases

early life
genome wide
depressive symptoms
single cell
sleep quality
case report
dna methylation
copy number
physical activity