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Identification and validation of a multivariable prediction model based on blood plasma and serum metabolomics for the distinction of chronic pancreatitis subjects from non-pancreas disease control subjects.

M Gordian AdamGeorg BeyerNicole ChristiansenBeate KamlageChristian PilarskyMarius DistlerTim FahlbuschAnsgar ChromikFritz KleinMarcus BahraWaldemar UhlRobert GrützmannUjjwal Mukund MahajanFrank Ulrich WeissJulia MayerleMarkus M Lerch
Published in: Gut (2021)
This is the first study that identifies and independently validates a metabolomic signature in plasma and serum for the diagnosis of CP in large, prospective cohorts. The results could provide the basis for the development of the first routine laboratory test for CP.
Keyphrases
  • mass spectrometry
  • genome wide
  • clinical practice