A duplex polymerase chain reaction-restriction fragment length polymorphism for rapid screening of methylenetetrahydrofolate reductase gene variants: Genotyping in acute leukemia.

Rim FrikhaNouha BouayedBochra Ben RhoumaLeila KeskesTarek Rebai

Published in: Journal of clinical laboratory analysis (2017)

This new method has proved to be a rapid, simple, and reliable method that should facilitate high throughput genotyping of MTHFR polymorphisms in acute leukemia.

Keyphrases

high throughput
genome wide
copy number
loop mediated isothermal amplification
single cell
dna methylation
genetic diversity
sensitive detection