Copaiba oil enhances in vitro/in vivo cutaneous permeability and in vivo anti-inflammatory effect of celecoxib.
Oliesia Gonzalez QuiñonesBryan Hudson HossyTatiana Almeida PaduaNádia Campos de Oliveira MiguelElaine Cruz RosasMônica Freiman de Souza RamosMaria Bernadete Riemma PierrePublished in: The Journal of pharmacy and pharmacology (2018)
25% C.O is a potential penetration enhancer for lipophilic drugs like Cxb that can improve cutaneous drug penetration and its anti-inflammatory activity.