Feasibility of using Clinical Practice Research Datalink data to identify patients with chronic obstructive pulmonary disease to enrol into real-world trials.

Gema RequenaAchim WolfRachael WilliamsDaniel DedmanJennifer K QuintTarita Murray-ThomasJeanne M Pimenta

Published in: Pharmacoepidemiology and drug safety (2021)

Patients and data from CPRD GOLD and CPRD Aurum were comparable across key aspects relevant to COPD trials. A pragmatic trial using CPRD to recruit patients with COPD is scientifically feasible.

Keyphrases

chronic obstructive pulmonary disease
clinical practice
end stage renal disease
electronic health record
lung function
study protocol
newly diagnosed
ejection fraction
chronic kidney disease
big data
clinical trial
phase iii
cystic fibrosis
phase ii
artificial intelligence
patient reported