Timing of gamma irradiation and blood donor sex influences in vitro characteristics of red blood cells.
Dirk de KorteLouis ThibaultWiebke HandkeSarah K HarmAlex MorrisonAine FitzpatrickDenese C MarksQi-Long YiJason P Ackernull nullPublished in: Transfusion (2018)
The method of blood component manufacturing determined the absolute levels of hemolysis and potassium in irradiated and nonirradiated units, but did not influence the effect that timing of irradiation had on the in vitro quality characteristics. This study provides support for the current Council of Europe guidelines on the time limitations for the irradiation of RBCs.