Case Report: Pulmonary sarcomatoid carcinoma in a female patient from Nepal.
Anirudra DevkotaAmrit PaudelSimit SapkotaSubash PanditAashish BaniyaPublished in: F1000Research (2021)
Sarcomatoid carcinoma of the lung is an uncommon subtype of non-small-cell lung cancer (NSCLC). Even in the early stages, pulmonary sarcomatoid carcinoma (PSC) has a dismal prognosis when compared to other kinds of NSCLC with a mean survival of 9-12 months and a five-year survival rate of around 20%. We present the case of a 68-year-old woman with a two-month history of shortness of breath and cough. Initial computed tomography (CT) scan showed features of interstitial lung disease with chronic obstructive airway changes. After 34 months, the patient's condition worsened with newer complaints of sore throat and hemoptysis. A repeat CT scan showed a ∼49x38x59mm size lesion in the superior segment of the left lower lobe. A core needle biopsy was performed, which revealed tumor cells consisting of irregular tubules and sarcomatoid components. The patient was started on chemotherapy. Unfortunately, she succumbed to her disease. Our case highlights the aggressiveness of PSC.
Keyphrases
- computed tomography
- case report
- dual energy
- interstitial lung disease
- positron emission tomography
- small cell lung cancer
- image quality
- contrast enhanced
- systemic sclerosis
- pulmonary hypertension
- magnetic resonance imaging
- ultrasound guided
- rheumatoid arthritis
- advanced non small cell lung cancer
- magnetic resonance
- idiopathic pulmonary fibrosis
- locally advanced
- tyrosine kinase