Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction.

JoAnne J BabulaDinh BuiHeather L StevensonStanley J WatowichHarshini Neelakantan

Published in: Diabetes, obesity & metabolism (2024)

This work validates NNMT inhibition as a viable pharmacological approach to ameliorate metabolic imbalances and improve liver pathologies that develop with obesity.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
oxidative stress
adipose tissue
radiation induced
physical activity
drug induced