Angiogenic and molecular diversity determine hepatic melanoma metastasis and response to anti-angiogenic treatment.
Sebastian A WohlfeilVerena HäfeleBianca DietschCéline WellerCarsten StichtAnna Sophia JauchManuel WinklerChristian David SchmidAnna Lena IrkensAna OlsavszkyKai SchledzewskiPhilipp-Sebastian Reiners-KochSergij GoerdtCyrill GéraudPublished in: Journal of translational medicine (2022)
Our data indicate that molecular heterogeneity of melanomas can be associated with phenotypic and prognostic features of hepatic metastasis paving the way for organ-specific anti-angiogenic therapeutic approaches.
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