The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin.

S BotticelliR ChiaraluceV ConsalviG La PennaA PasquoM PetrosinoO ProuxG C RossiF StellatoSilvia Morante

Published in: European physical journal plus (2023)

In this paper, we provide evidence that Zn 2 + ions play a role in the SARS-CoV-2 virus strategy to escape the immune response mediated by the BST2-tetherin host protein. This conclusion is based on sequence analysis and molecular dynamics simulations as well as X-ray absorption experiments [1].

Keyphrases

sars cov
molecular dynamics simulations
immune response
respiratory syndrome coronavirus
amino acid
heavy metals
protein protein
quantum dots
high resolution
binding protein
aqueous solution
toll like receptor
magnetic resonance
computed tomography
risk assessment
dual energy
coronavirus disease