Correction of Vascular Calcification and Hyperphosphatemia in CKD Rats Treated with ASARM Peptide.
Peter S RoweEllen M McCarthyAlan S L YuJason R StubbsPublished in: Kidney360 (2022)
ASARM peptide infusion corrects hyperphosphatemia and improves vascular calcification, renal calcification, brain calcification, bone quality, renal function, and skin mineralization abnormalities in 56NEPHREX rats. These findings confirm our hypothesis and support the utility of ASARM peptide treatment in patients with CKD-MBD.