Treatment regimens and outcomes in severe and moderate haemophilia A in the UK: The THUNDER study.
Martin J ScottHua XiangDaniel P HartBenedict PalmerPeter W CollinsDavid StephensenCamelia S SimaCharles R M HayPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2018)
Increasing ABR with age persists despite current prophylaxis regimens. SHA and MHA had similar ABR/AJBR and HJHS, leading to a suspicion that a subgroup of MHA may be relatively undertreated. More intensive prophylaxis may improve outcomes, but this requires further study.