Threat and reward imminence processing in the human brain.

Dinavahi V P S Murty Songtao Song Srinivas Govinda Surampudi Luiz Pessoa

Published in: bioRxiv : the preprint server for biology (2023)

. We uncovered imminence-related temporally increasing ("ramping") responses in multiple brain regions, including the bed nucleus of the stria terminalis, periaqueductal gray, and ventral striatum, subcortically, and dorsal anterior insula and anterior midcingulate, cortically. Overall, we uncovered extensive temporally-evolving, imminence-related processing in both the aversive and appetitive domain, suggesting that distributed brain circuits are dynamically engaged during the processing of biologically relevant information irrespective of valence.

Keyphrases

resting state
spinal cord
functional connectivity
white matter
prefrontal cortex
neuropathic pain
cerebral ischemia
multiple sclerosis
spinal cord injury
health information
brain injury
neural network
drug induced